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TopoGen成立于1991年，是一家總部位于美國的生物技術(shù)公司，專注于拓撲異構(gòu)酶研究。公司致力于為藥物開發(fā)和機制研究提供創(chuàng)新的產(chǎn)品和服務，尤其在癌癥化療和抗菌藥物研發(fā)領(lǐng)域。
主要產(chǎn)品線及特點
TopoGen的主要產(chǎn)品線包括：
Topo Kits：提供多種與拓撲異構(gòu)酶相關(guān)的試劑盒，用于研究和藥物篩選。
DNA修復報告細胞系：用于藥物發(fā)現(xiàn)，特別是那些可能通過影響DNA修復途徑來增強腫瘤細胞殺傷效果的藥物。
DNA載體和裂解目標：提供用于DNA相關(guān)研究的載體和裂解目標。
拓撲異構(gòu)酶抑制劑：用于研究和藥物開發(fā)，特別是在癌癥治療領(lǐng)域。
拓撲異構(gòu)酶抗體：用于科研和臨床診斷，特別是在檢測和研究拓撲異構(gòu)酶相關(guān)疾病方面。
產(chǎn)品優(yōu)勢
TopoGen的產(chǎn)品以其高質(zhì)量、創(chuàng)新性和專業(yè)性著稱。公司提供獨立驗證、快速服務和價值，以及保護客戶研究成果的保密協(xié)議。TopoGen還提供Turn-Key合同服務，以篩選新的拓撲異構(gòu)酶藥物，作為經(jīng)驗豐富 的合同研究組織，擁有眾多優(yōu)勢。
熱門產(chǎn)品介紹
Human Topoisomerase II Assay Kit（人拓撲異構(gòu)酶II檢測試劑盒）
產(chǎn)品特點：用于分析拓撲異構(gòu)酶II活性的藥物篩選。
貨號：TG1001-1。
應用領(lǐng)域：廣泛應用于癌癥研究和藥物開發(fā)。
Topoisomerase I Drug Screening Kit（拓撲異構(gòu)酶I藥物篩選試劑盒）
產(chǎn)品特點：專門用于篩選影響拓撲異構(gòu)酶I活性的藥物。
貨號：TG1018-1。
應用領(lǐng)域：適用于抗癌藥物的研發(fā)。
Monoclonal Antibody to Human Topoisomerase II Alpha（人拓撲異構(gòu)酶IIα單克隆抗體）
產(chǎn)品特點：高特異性單克隆抗體，用于檢測人類拓撲異構(gòu)酶IIα。
貨號：TG2010-1。
應用領(lǐng)域：適用于基礎研究和臨床診斷。
公司競爭優(yōu)勢
TopoGen的競爭優(yōu)勢在于其專業(yè)的研發(fā)團隊和豐富的產(chǎn)品線。公司擁有先進的活細胞測試技術(shù)和雙重凝膠分析系統(tǒng)，能夠為客戶提供深入的化合物分析。此外，TopoGEN的合同研究組織（CRO）服務能夠快速響應客戶需求，提供高效的實驗室支持。
客戶人群
TopoGen的客戶主要包括全球的大學和研究機構(gòu)、藥物開發(fā)公司、臨床研究機構(gòu)以及生物技術(shù)公司。這些客戶利用TopoGen的產(chǎn)品進行基礎和應用研究，特別是在癌癥和抗感染藥物的研發(fā)方面。
社會責任與可持續(xù)發(fā)展
TopoGen積極履行社會責任，致力于可持續(xù)發(fā)展。公司在生產(chǎn)過程中遵循環(huán)保原則，努力減少對環(huán)境的影響，并通過技術(shù)創(chuàng)新推動行業(yè)的可持續(xù)發(fā)展。TopoGen還注重與客戶的合作，確保研究成果的保密性和安全性，以促進科學研究的進步。
熱賣產(chǎn)品
| 貨號 | 品名 | 規(guī)格 | 品牌 |
| TG2014 | Rabbit Polyclonal Antibody to Yeast Topo II (Serum) | 250ul | topogen |
| TG1005-2 | Human TDP2 Assay Kit | 250assays | topogen |
| TG1005-1 | Human TDP2 Assay Kit | 100assays | topogen |
| TG2038-1 | Human TDP2 DNA Substrate | 10ug | topogen |
| TG2038-3 | Human TDP2 DNA Substrate | 50ug | topogen |
| TG2000G-7 | E. coli DNA Gyrase | 2000units | topogen |
| TG1009-1A | Topoisomerase II Drug Screening Kit (25ug SC DNA + 100u Topo Iia) | 100 Assays + 100 Units Enzyme | topogen |
| TG1020-1 | Human Topoisomerase I ICE Assay Kit | 24Tests | topogen |
| TG1020-0 | Human Topoisomerase I ICE Assay Kit (No Antibody) | 24Tests | topogen |
| DR5000A-CUSTOM-SCE | Custom Cell Based Screening for NHEJ Repair | 25assays(no cell line included) | topogen |
| TG2000G-1 | E. coli DNA Gyrase | 100units | topogen |
| TG2000EC-1 | E. coli Topoisomerase IV | 250units | topogen |
| DR3000Custom-Sce | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) Includes HRHeLa cell line control (50ug DNA) | 25assays | topogen |
| TG1009-3A | Topoisomerase II Drug Screening Kit (62.5ug SC DNA + 500u Topo Iia) | 250assays | topogen |
| TG2005H-Y723F | Mutant Human Topoisomerase I (Y723F) | 10ug | topogen |
| TG2000GSA-3 | S. aureus DNA Gyrase | 500units | topogen |
| TG2000G-3 | E. coli DNA Gyrase | 500units | topogen |
| TG2000EC-3 | E. coli Topoisomerase IV | 500units | topogen |
| TG4030 | Gyrase Assay Buffer 5x | 1ml | topogen |
| TG2020-1 | Decatenated Kinetoplast DNA Marker | 10ug | topogen |
| TG2018-1 | Linear Kinetoplast DNA Marker | 10ug | topogen |
| TOP-TG2000G-1KIT | E. coli DNA Gyrase and Relaxed DNA Assay Kit | 100 Assays | topogen |
| TOP-TG1003 | DNA Gyrase Assay Kit | 1x100 assays | topogen |
| DR-3000A-Custom-Sce3 | Custom Cell Based Screening Kit for (HR) Pathway | 125 Assays (no cell line included) | topogen |
| DR3000ACustom-Sce2 | Custom Cell Based Screening Kit for (HR) Pathway | 50 Assays (no cell line included) | topogen |
| DR3000ACustom-Sce | Custom Cell Based Screening Kit for (HR) Pathway | 25 Assays (no cell line included) | topogen |
| TG2015 | Monoclonal Antibody to Human Topoisomerase III Alpha | 50ul | topogen |
| TG2011-4 | Topoisomerase I WB Marker | 20units | topogen |
| TGi015-1 | Human Topoisomerase I Assay Kit | 100assays | topogen |
| TG1019-1 | Topoisomerase II Drug Screening Kit (kDNA based) | 1x100 assays | topogen |
| TG4040 | Topo II Assay Buffer (2 part) | 1ml | topogen |
| TG1019-2 | Topoisomerase II Drug Screening Kit (kDNA based) | 250 Assays | topogen |
| TG4090 | Topoisomerase II Dilution Buffer | 1ml | topogen |
| TG2013-3 | Kinetoplast DNA (catenated) | 250ug | topogen |
| TG1019-1A | Topoisomerase II Drug Screening Kit (kDNA based) | 100 Assays + 100 Units Enzyme | topogen |
| TG2013-1 | Kinetoplast DNA (catenated) | 25ug | topogen |
| TG4110 | Camptothecin 10mM | 0.25ml | topogen |
| TG1018-3A | Topoisomerase I Drug Screening Kit | 250 Assays + 500 Units Enzyme | topogen |
| TG1018-2A | Topoisomerase I Drug Screening Kit | 250 Assays + 250 Units Enzyme | topogen |
| TG1018-1A | Topoisomerase I Drug Screening Kit | 100 Assays + 100 Units Enzyme | topogen |
| TG1018-2 | Topoisomerase I Drug Screening Kit | 250 Assays | topogen |
| TG2013-2 | Kinetoplast DNA (kDNA) | 50ug | topogen |
| TG1001-3A | Human Topoisomerase II Assay Kit | 500 Assays + 500 Units Enzyme | topogen |
| TG1001-2A | Human Topoisomerase II Assay Kit | 250 Assays + 250 Units Enzyme | topogen |
| TG1001-1A | Human Topoisomerase II Assay Kit | 100 Assays + 100 Units Enzyme | topogen |
| TG1001-2 | Human Topoisomerase II Assay Kit | 250 Assays | topogen |
| TG1001-1 | Human Topoisomerase II Assay Kit | 100 Assays | topogen |
| TG2000H-4 | Human Topoisomerase IIα | 2000 Units | topogen |
| TG2000H-3 | Human Topoisomerase IIα | 1000 Units | topogen |
| TG2000H-2 | Human Topoisomerase IIα | 500 Units | topogen |
| TG1015-3A | Human Topoisomerase I Assay Kit | 500 Assays + 500 Units Enzyme | topogen |
| TG1015-2 | Human Topoisomerase I Assay Kit | 250 Assays | topogen |
| TG1015-1 | Human Topoisomerase I Assay Kit | 100 Assays | topogen |
| TG2005H-RC3 | Human Topoisomerase I (T0p1) | 3000 Units | topogen |
| TG4037 | 5X Universal Stop Buffer | 1ml | topogen |
| TG2005H-RC2 | Human Topoisomerase I | 500 units | topogen |
| TG1018-1 | Topoisomerase I Drug Screening Kit | 100assays | topogen |
| TG1015-1A | Topoisomerase I Assay Kit (25ug SC DNA +100u Human Topo I) | 100assays | topogen |
| TG1015-2A | Human Topoisomerase I Assay Kit | 250 Assays + 250 Units Enzyme | topogen |
| TG2005H-RC1 | Human Topoisomerase I (T0p1) | 250 Units | topogen |
| TG1009-1 | Topoisomerase II Drug Screening Kit (25ug SC DNA) | 100 assays | topogen |
| TG2000H-1 | Human Topoisomerase IIα | 250 Units | topogen |
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